From SciTechDaily
A new Brazilian study published in the scientific journal Molecular and Cellular Endocrinology has identified a critical role for the protein periostin and stellate pancreatic cells in enabling pancreatic cancer to invade nerves and spread at an early stage, raising the likelihood of metastasis.
The findings show that the tumor actively alters nearby healthy tissue to gain a strong invasive ability. This process helps explain why the disease is so aggressive and hard to treat, while also highlighting potential targets for more precise and personalized therapies.