By Tom Dinki – SciTechDaily
L-arginine helps protein droplets stay stable and prevents fibril formation linked to Alzheimer’s. This process occurs at droplet surfaces, offering a potential therapeutic target.
Inside living cells, tiny liquid-like droplets quietly keep essential processes running. But in disorders like Alzheimer’s, these dynamic structures can take a dangerous turn, hardening into fiber-like fibrils that disrupt the inner workings of neurons.
This transformation undermines critical functions, including the stabilization of microtubules that ferry vital cargo through cells. The challenge has been finding a way to stop this harmful shift without shutting down the droplets’ normal activity.